This may not be that much of a surprise but Mississippi State is favored to beat Southern Miss. Betting service 5Dimes released their lines for opening week games and the Bulldogs are favored to beat the Golden Eagles by 23.5 points. The over/under is 51.5 points.
In their 2014 meeting, State drubbed USM 49-0 and it's in no way unreasonable to expect a similar outcome in 2015. MSU kicks off against Southern Miss September 5th in Hattiesburg, MS at 9 P.M. CST on Fox Sports 1.
Here's the full list of opening weekend lines from 5Dimes from around the SEC:
South Carolina -5.5 vs. North Carolina
Texas A&M -4 vs. Arizona State (in Houston)
Florida -35.5 vs. New Mexico State
Georgia -36 vs. UL Monroe
Kentucky -13.5 vs. UL Lafayette
Tennessee -24.5 vs. Bowling Green (in Nashville)
Vanderbilt -1.5 vs. Western Kentucky
Arkansas -34.5 vs. UTEP
Auburn -13 vs. Louisville (in Atlanta)
Alabama -13 vs. Wisconsin (in Arlington)